Product overview

Name AACOCF3
Alternative names Arachidonyl trifluoromethyl ketone
Description Selective cPLA2 inhibitor
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Biological Data

Biological description Selective cytosolic phospholipase A2 inhibitor (IC50 values are 1.5 and 6.0 µM for bovine brain cPLA2 and iPLA2 respectively). Also inhibits FAAH. Displaces [3H]CP-55940 binding to CB1 receptor (Ki = 0.65 µM). Increases aldosterone and corticosterone secretion.

Solubility & Handling

Storage instructions -20°C (desiccate)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Chemical Data

Chemical name 1,1,1-Trifluoro-6Z,9Z,12Z,15Z-henei cosateraen-2-one
Molecular Weight 356.47
Chemical structure AACOCF3? Chemical Structure
Molecular Formula C21H31F3O
CAS Number 149301-79-1
PubChem identifier 5280436
SMILES O=C(C(F)(F)F)CCC\C=C/C\C=C/C/C=C\C/C=C\CCCCC
InChiKey PLWROONZUDKYKG-DOFZRALJSA-N