Acamprosate calcium

(HB0099)

Product overview

  • Name
    Acamprosate calcium
  • Short description
    GABA receptor agonist and glutamergic modulator
  • Biological description
    GABA receptor agonist. Also acts as NMDA receptor and mGluR5 antagonist. Taurinate analog. Reduces alcohol addiction in various animal models. Displays neuroprotective properties.
  • Alternative names
    Calcium acetylhomotaurinate | Campral
  • Biological action
    Agonist
  • Our products in action

Properties

  • Chemical name
    3-(Acetylamino)-1-propanesulfonic acid hemicalcium salt
  • Molecular Weight
    200.24
  • Chemical structure
    Acamprosate calcium  [77337-73-6]
  • Molecular Formula
    C5H10NO4S.½ Ca
  • CAS Number
    77337-73-6

Storing and Using Your Product

  • Storage instructions
    room temperature (desiccate)
  • Solubility overview
    soluble in water (100mM)

References for Acamprosate calcium

  • Neuroprotective and abstinence-promoting effects of acamprosate: elucidating the mechanism of action.

    De Witte P et al (2005) CNS Drugs 19(6) : 517-37.
    PubMedID: 15963001
  • Acamprosate enhances N-methyl-D-apartate receptor-mediated neurotransmission but inhibits presynaptic GABA(B) receptors in nucleus accumbens neurons.

    Berton F et al (1998) Alcohol Clin Exp Res 22(1) : 183-91.
    PubMedID: 9514305