Estrogen receptor agonists and antagonists...low cost, high quality

estrogen receptor research tools

Estrogen modulates many cellular processes including growth, differentiation and function of the reproductive system. Estrogen receptors include:

  • estrogen receptors ERα and ERβ, which are ligand-activated transcription factors belonging to the nuclear hormone receptor superfamily. Both receptors interact with the same DNA response element and have a similar pharmacological profile.
  • estrogen-related receptors (ERRs): ERRα, ERRβ and ERRγ. These are activated by co-regulatory proteins and bind the ERE and ERR response elements (ERREs) as homodimers, exerting transcriptional control of energy homeostasis.
  • the G protein-coupled estrogen receptor (GPER, GPR30) which is a seven transmembrane spanning receptor that couples to heterotrimeric Gs-proteins. It functions independently from ERα or ERβ estrogen receptors. The GPER binds estradiol with high affinity, but has lower affinity for estrone and estriol.

As a specialist supplier of affordable estrogen receptor research tools, Hello Bio has introduced a range of low cost agonists and antagonists for estrogen receptors - at prices up to 50% less than other suppliers. Our range includes tools such as ICI 182780, an estrogen receptor (ER) antagonist and high affinity GPER agonist, and tamoxifen citrate. ERα selective tools include ERα agonist PPT, and ERα antagonist MPP. Our range of ERβ selective ligands include ERβ agonist DPN and ERβ antagonist PHTPP

Browse our full range of estrogen receptor agonists and antagonists below:

High quality

Our prices are up to 50% less than other suppliers (check our price comparison table). However, we know that product reliability is more important than price. We are based in purpose built labs in the UK and with decades of synthetic and manufacturing chemistry expertise we know what we are doing! For your peace of mind, all of our products are covered by the Hello BioPromise quality guarantee.

Most popular estrogen receptor and signaling related ranges