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Prostaglandin E2

(HB3460)
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Technical documents: SDS CoA Datasheet

Product overview

Name Prostaglandin E2
Alternative names Dinoprostone | PGE2
Purity >98%
Description Endogenous prostanoid. Induces hematopoietic stem cell proliferation. 3D growth matrix component and used in production of liver and prostate organoids.
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (2) Reviews References (4) Frequently bought together
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Biological Data

Biological description

Endogenous prostanoid (Kd values are ~1-10 nM at EP1, EP2, EP3 and EP4 which shows many biological actions and modulates various pathological and physiological activities.

It induces hematopoietic stem cell (HSC) proliferation. It can be a used as a 3D growth matrix component and used in production of liver and prostate organoids.

Solubility & Handling

Storage instructions -20°C
Solubility overview Soluble in DMSO (100mM) or ethanol (45mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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x
More Info

Dilution

x
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x
More Info

Chemical Data

Purity >98%
Chemical name (5Z,11α,13E,15S)-11,15-Dihydroxy-9-o xo-prosta-5,13-dien-1oic acid
Molecular Weight 352.47
Chemical structure Prostaglandin E2 | [363-24-6] Chemical Structure
Molecular Formula C20H32O5
CAS Number 363-24-6
PubChem identifier 5280360
SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O
InChiKey XEYBRNLFEZDVAW-ARSRFYASSA-N

References for Prostaglandin E2

References are publications that support the biological activity of the product

  • The multiple faces of prostaglandin E2 G-protein coupled receptor signaling during the dendritic cell life cycle.

    De Keijzer et al (2013) Int J Mol Sci 14(4) : 6542-55
    Read more (PubMedID: 23528886)

  • Roles of prostaglandin E2 in cardiovascular diseases.

    Suzuki et al (2011) Int Heart J 52(5) : 266-9
    Read more (PubMedID: 22008433)

  • Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis.

    North et al (2007) Nature 447(7147) : 1007-11
    Read more (PubMedID: 17581586)

  • International Union of Pharmacology classification of prostanoid receptors: properties, distribution, and structure of the receptors and their subtypes.

    Coleman et al (1994) Pharmacol Rev 46(2) : 205-29
    Read more (PubMedID: 7938166)

4 Item(s)

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Grouped product items
Order: HB3460
Pack PriceQty
10mg
$160
Endogenous prostanoid. Induces hematopoietic stem cell proliferation. 3D growth matrix component and used in production of liver and prostate organoids.
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