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Raloxifene hydrochloride

(HB2509)
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Technical documents: Datasheet

Product overview

Name Raloxifene hydrochloride
Alternative names LY 139481, Keoxifene
Purity >98%
Description Selective estrogen receptor modulator
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (3)
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Biological Data

Biological description Selective estrogen receptor modulator (Ki values are 0.38 and 5.6 nM at Erα and Erβ respectively). Shows estrogenic activity in bone and anti-estrogenic activity in breast tissue. Also shows antitumor and autophagy inducing effects. Active in vivo.

Solubility & Handling

Storage instructions +4°C (desiccate)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >98%
Chemical name [6-Hydroxy-2-(4-hydroxyphenyl)benzo [b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]-methanone hydrochloride
Molecular Weight 510.04
Chemical structure Raloxifene hydrochloride Chemical Structure
Molecular Formula C28H27NO4S.HCl
CAS Number 82640-04-8
PubChem identifier 54900
SMILES Cl.OC1=CC=C(C=C1)C1=C(C(=O)C2=CC=C(OCCN3CCCCC3)C=C2)C2=CC=C(O)C=C2S1
InChiKey BKXVVCILCIUCLG-UHFFFAOYSA-N

References for Raloxifene hydrochloride

References are publications that support the biological activity of the product

  • Raloxifene Induces Autophagy-Dependent Cell Death in Breast Cancer Cells via the Activation of AMP-Activated Protein Kinase.

    Kim DE et al (2015) Mol Cells 38(2) : 138-44.
    Read more (PubMedID: 25537862)

  • Antagonists selective for estrogen receptor alpha.

    Sun J et al (2002) Endocrinology 143(3) : 941-7.
    Read more (PubMedID: 11861516)

  • Mechanism of action and preclinical profile of raloxifene, a selective estrogen receptor modulation.

    Bryant HU (2001) Rev Endocr Metab Disord 2(1) : 129-38.
    Read more (PubMedID: 11704975)

3 Item(s)

Grouped product items
Order: HB2509
Pack PriceQty
50mg
$109
Selective estrogen receptor modulator
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

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