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Product overview

  • Name
  • Short description
    PKC inhibitor
  • Biological description
    Protein kinase C (PKC) inhibitor, acts as a diacylglycerol (DAG) antagonist. Synthetic precursor of platelet activating factor (PAF). Shows growth inhibitory actions against the promyelocytic leukemia cell line.
  • Biological action
  • Purity
  • Citations


  • Molecular Weight
  • Chemical structure
    1-O-Hexadecyl-2-O-acetyl-sn-glycerol  [77133-35-8]
  • Molecular Formula
  • CAS Number

Storing and Using Your Product

  • Solubility overview
    soluble in ethanol or acetone
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for 1-O-Hexadecyl-2-O-acetyl-sn-glycerol

  • Activation of corticotropin-releasing factor 2 receptor inhibits Purkinje neuron P-type calcium currents via G(o)alpha-dependent PKC epsilon pathway.

    Tao J et al (2009) Cell Signal 21(9) : 1436-43.
    PubMedID: 19439178
  • Amyloid-beta42 signals tau hyperphosphorylation and compromises neuronal viability by disrupting alkylacylglycerophosphocholine metabolism.

    Ryan SD et al (2009) Proc Natl Acad Sci U S A 106(49) : 20936-41.
    PubMedID: 19926863
  • 1-O-alkyl-2-acetyl-sn-glycerol: a platelet-activating factor metabolite with biological activity in vascular smooth muscle cells.

    Stoll LL et al (1989) Cell Regul 1(1) : 13-25.
    PubMedID: 2519612
  • 1-0-Hexadecyl-2-acetyl-sn-glycerol stimulates differentiation of HL-60 human promyelocytic leukemia cells to macrophage-like cells.

    McNamara MJ et al (1984) Biochem Biophys Res Commun 122(2) : 824-30.
    PubMedID: 6590040
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