17-AAG

(HB3599)

Product overview

  • Name
    17-AAG
  • Short description
    Selective Hsp90 inhibitor. Also protects neuroprogenitor cells against apoptosis.
  • Biological description
    Selective Hsp90 inhibitor. Potent, less toxic analog of geldanamycin. Also a telomerase activity inhibitor. Shows antitumor activity and induces apoptosis. Also protects neuroprogenitor cells against apoptosis.
  • Alternative names
    Tanespimycin
  • Biological action
    Antibiotic
  • Purity
    >98%
  • Citations

Properties

  • Chemical name
    17-Demethoxy-17-(2-propenylamino)geldanamycin
  • Molecular Weight
    585.7
  • Molecular Formula
    C31H43N3O8
  • CAS Number
    75747-14-7
  • PubChem identifier
    433449
  • SMILES
    CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCC=C)C)OC)OC(=O)N)C)C)O)OC
  • InChiKey
    AYUNIORJHRXIBJ-TXHRRWQRSA-N
  • MDL number
    MFCD04973892
  • Appearance
    Purple

Storing and Using Your Product

  • Storage instructions
    -20 °C;
  • Solubility overview
    Soluble in DMSO (100 mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.