5-HT receptor research tools...low cost, high quality
5-HT or serotonin receptors are classified into seven distinct families (5-HT1-7) based on their pharmacological profiles, similar amino acid sequences, structural properties and signal transduction mechanisms. Further 5-HT receptor heterogeneity is generated through alternative splicing (5-HT3, 5-HT4 and 5-HT7 receptors), RNA editing (5-HT2C receptors) and the putative formation of heterodimers (e.g. the 5-HT4 receptor with the beta-2 adrenoreceptor). 5-HT1, 5-HT2, 5-HT4, 5-HT5, 5-HT6 and 5-HT7 are G protein coupled receptors, whereas the 5-HT3 receptor is a ligand-gated ion channel of the Cys-loop family that includes the zinc-activated channels, nicotinic acetylcholine, GABAA and strychnine-sensitive glycine receptors.
As a specialist supplier of affordable 5HT receptor research tools, Hello Bio has introduced a range of low cost agonists, antagonists, modulators and fluorescent tools for 5-HT receptors - at prices up to 50% less than other suppliers. Our range includes tools such as potent serotonin reuptake blocker fluoxetine and SB 269970 a potent, selective 5-HT7 receptor antagonist.
Browse our range of 5-HT receptor agonists, antagonists and uptake modulators below: :
|5-HT1 receptor||5-HT2 receptor||5-HT3 receptors
5-HT uptake modulators
Fluorescent 5-HT tools
Our prices are up to 50% less than other suppliers (check our price comparison table). However, we know that product reliability is more important than price. We are based in purpose built labs in the UK and with decades of synthetic and manufacturing chemistry expertise we know what we are doing! For your peace of mind, all of our products are covered by the Hello BioPromise quality guarantee.
Featured 5-HT receptor related products
Cmpd101 is a novel, potent and selective G-protein coupled receptor kinase 2 and 3 (GRK2/GRK3) inhibitor (IC50 values are 35, 290 nM and 125 µM at GRK2, GRK3 and GRK5 respectively). It shows little activity at a broad range of other kinases. Membrane permeable, it can be used to study the roles of GRK2/3 in GPCR desensitization and other functions. Find out more…CellAura fluorescent 5-HT1A antagonist [NAN-190]
Fluorescent 5-HT1A serotonin receptor antagonist (apparent KD values are 8.75, 6.34 and 5.57 for 5-HT1A, 5-HT2A and 5-HT1B receptors respectively). Antagonizes the activity of serotonin, a 5-HT1A agonist. Find out more...
GBR 12909 dihydrochloride is a potent, competitive dopamine uptake inhibitor.