7-Oxostaurosporine

(HB0088)

Product overview

  • Name
    7-Oxostaurosporine
  • Short description
    PKC inhibitor
  • Biological description
    Protein kinase C (PKC) inhibitor. Inhibits cell cycle progression (G2 phase) and bleb formation. More potent than staurosporine. Displays antimicrobial, antiproliferative and antitumor properties.
  • Biological action
    Inhibitor
  • Purity
    >98%
  • Our products in action

Properties

  • Molecular Weight
    480.5
  • Chemical structure
    7-Oxostaurosporine  [141196-69-2]
  • Molecular Formula
    C28H24N4O4
  • CAS Number
    141196-69-2
  • PubChem identifier
    10906957
  • SMILES
    C[C@@]12[C@@H]([C@@H](C[C@@H](O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)C(=O)NC6=O)NC)OC

Storing and Using Your Product

  • Solubility overview
    soluble in DMSO or DMF
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for 7-Oxostaurosporine

  • A new inhibitor of protein kinase C, RK-1409 (7-oxostaurosporine). I. Taxonomy and biological activity.

    Osada H et al (1992) J Antibiot (Tokyo) 45(2) : 189-94.
    PubMedID: 1556009
  • A new inhibitor of protein kinase C, RK-1409 (7-oxostaurosporine). II. Fermentation, isolation, physico-chemical properties and structure.

    Koshino H et al (1992) J Antibiot (Tokyo) 45(2) : 195-8.
    PubMedID: 1556010
  • Structure elucidation and anticancer activity of 7-oxostaurosporine derivatives from the Brazilian endemic tunicate Eudistoma vannamei.

    Jimenez PC et al (2012) Mar Drugs 10(5) : 1092-102.
    PubMedID: 22822359

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