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Product overview

  • Name
  • Short description
    Selective calmodulin-dependent PDE-1 inhibitor
  • Biological description
    Selective calmodulin-dependent phosphodiesterase 1 (PDE-1) inhibitor. Increases Ca2+-activated K+ (BK) channel activity in the urinary bladder and shows smooth muscle relaxing actions. Also shows vasodilator actions.
  • Alternative names
  • Biological action
  • Purity
  • Citations


  • Molecular Weight
  • Chemical structure
    8-Methoxymethyl-IBMX  [78033-08-6]
  • Molecular Formula
  • CAS Number
  • PubChem identifier

Storing and Using Your Product

  • Storage instructions
    room temperature
  • Solubility overview
    soluble in ethanol or DMOS (5mg/ml)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for MMPX

  • Effects of selective inhibitors on cyclic nucleotide phosphodiesterases of rabbit aorta.

    Ahn HS et al (1989) Biochem Pharmacol 38(19) : 3331-9.
    PubMedID: 2554921
  • Selective inhibition of phosphodiesterase 1 relaxes urinary bladder smooth muscle: role for ryanodine receptor-mediated BK channel activation.

    Xin W et al (2012) Am J Physiol Cell Physiol 303(10) : C1079-89.
    PubMedID: 22992675
  • In vivo effects of phosphodiesterase inhibition on basal cyclic guanosine monophosphate levels in the prefrontal cortex, hippocampus and cerebellum of freely moving rats.

    Marte A et al (2008) J Neurosci Res 86(15) : 3338-47.
    PubMedID: 18655195
  • Lung vasodilatory response to inhaled iloprost in experimental pulmonary hypertension: amplification by different type phosphodiesterase inhibitors.

    Schermuly RT et al (2005) Respir Res 6 : 76
    PubMedID: 16033645
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