Pack	Price	Qty
10mg	$264
50mg	$1,053

MMPX

(HB0092)

Product overview

Name
MMPX
Short description
Selective calmodulin-dependent PDE-1 inhibitor
Biological description
Selective calmodulin-dependent phosphodiesterase 1 (PDE-1) inhibitor. Increases Ca²⁺-activated K⁺ (BK) channel activity in the urinary bladder and shows smooth muscle relaxing actions. Also shows vasodilator actions.
Alternative names
8-Methoxymethyl-IBMX
Biological action
Inhibitor
Purity
>98%
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Storage instructions
room temperature
Solubility overview
soluble in ethanol or DMOS (5mg/ml)
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Effects of selective inhibitors on cyclic nucleotide phosphodiesterases of rabbit aorta.
Ahn HS et al (1989) Biochem Pharmacol 38(19) : 3331-9.
PubMedID: 2554921
Selective inhibition of phosphodiesterase 1 relaxes urinary bladder smooth muscle: role for ryanodine receptor-mediated BK channel activation.
Xin W et al (2012) Am J Physiol Cell Physiol 303(10) : C1079-89.
PubMedID: 22992675
In vivo effects of phosphodiesterase inhibition on basal cyclic guanosine monophosphate levels in the prefrontal cortex, hippocampus and cerebellum of freely moving rats.
Marte A et al (2008) J Neurosci Res 86(15) : 3338-47.
PubMedID: 18655195
Lung vasodilatory response to inhaled iloprost in experimental pulmonary hypertension: amplification by different type phosphodiesterase inhibitors.
Schermuly RT et al (2005) Respir Res 6 : 76
PubMedID: 16033645