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Product overview

  • Name
  • Short description
    Competitive NMDA receptor partial agonist
  • Biological description
    Competitive NMDA receptor partial agonist (Ki = 0.83 mM). Binds at glycine site. Shows 65-fold higher affinity for GluN3 compared to GluN1 subunit.
  • Biological action
  • Citations


  • Chemical name
    1-Aminocyclobutane-1-carboxylic acid
  • Molecular Weight
  • Chemical structure
    ACBC  [22264-50-2]
  • Molecular Formula
  • CAS Number

Storing and Using Your Product

  • Storage instructions
    room temperature
  • Solubility overview
    soluble in water (100mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for ACBC

  • Pharmacology of NMDA Receptors

    Monaghan DT et al (2009) 0 :
    PubMedID: 21204415
  • Mechanism of partial agonist action at the NR1 subunit of NMDA receptors.

    Inanobe A et al (2005) Neuron 47(1) : 71-84.
    PubMedID: 15996549
  • 1-Aminocyclobutane-1-carboxylate (ACBC): a specific antagonist of the N-methyl-D-aspartate receptor coupled glycine receptor.

    Hood WF et al (1989) Eur J Pharmacol 161(2-3) : 281-2.
    PubMedID: 2542048
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