Product overview

  • Name
    ACBC
  • Short description
    Competitive NMDA receptor partial agonist
  • Biological description
    Competitive NMDA receptor partial agonist (Ki = 0.83 mM). Binds at glycine site. Shows 65-fold higher affinity for GluN3 compared to GluN1 subunit.
  • Biological action
    Agonist
  • Our products in action

Properties

  • Chemical name
    1-Aminocyclobutane-1-carboxylic acid
  • Molecular Weight
    115.13
  • Chemical structure
    ACBC  [22264-50-2]
  • Molecular Formula
    C5H9NO2
  • CAS Number
    22264-50-2

Storing and Using Your Product

  • Storage instructions
    room temperature
  • Solubility overview
    soluble in water (100mM)

References for ACBC

  • Pharmacology of NMDA Receptors

    Monaghan DT et al (2009) 0 :
    PubMedID: 21204415
  • Mechanism of partial agonist action at the NR1 subunit of NMDA receptors.

    Inanobe A et al (2005) Neuron 47(1) : 71-84.
    PubMedID: 15996549
  • 1-Aminocyclobutane-1-carboxylate (ACBC): a specific antagonist of the N-methyl-D-aspartate receptor coupled glycine receptor.

    Hood WF et al (1989) Eur J Pharmacol 161(2-3) : 281-2.
    PubMedID: 2542048