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Actinomycin D

(HB1477)
Data

Product overview

  • Name
    Actinomycin D
  • Short description
    RNA polymerase inhibitor
  • Biological description
    RNA polymerase inhibitor and RNA synthesis inhibitor. DNA intercalating agent. Shows antitumor and cytotoxic effects. Also induces apoptosis.
  • Biological action
    Antibiotic
  • Applications
    Antineoplastic Agent, Cell Culture, Selection Agent
  • Purity
    >98%
  • Citations

Properties

  • Chemical name
    2-Amino-(N,N)-1-bis(hexadecahydro-6,13-diisopropyl-2,5,9-trimethyl-1,4,7,11,14-pentaoxo-1H-pyrrolo[2,1]-[1,4,7,10,13] oxatetraazacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide
  • Molecular Weight
    1255.43
  • Molecular Formula
    C62H86N12O16
  • CAS Number
    50-76-0
  • PubChem identifier
    2019
  • SMILES
    CC1C(C(=O)NC(C(=O)N2CCCC2C(=O)N(CC(=O)N(C(C(=O)O1)C(C)C)C)C)C(C)C)NC(=O)C3=C4C(=C(C=C3)C)OC5=C(C(=O)C(=C(C5=N4)C(=O)NC6C(OC(=O)C(N(C(=O)CN(C(=O)C7CCCN7C(=O)C(NC6=O)C(C)C)C)C)C(C)C)C)N)C
  • InChiKey
    RJURFGZVJUQBHK-LIAOQTPJSA-N
  • MDL number
    MFCD00005033
  • Appearance
    Red shiny crystals

Storing and Using Your Product

  • Storage instructions
    +4°C
  • Solubility overview
    Soluble in DMSO (50 mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
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