Amastatin hydrochloride

(HB3757)

Product overview

  • Name
    Amastatin hydrochloride
  • Short description
    Competitive aminopeptidase (AP) inhibitor
  • Biological description
    Slow, tight binding and competitive aminopeptidase (AP) inhibitor. Inhibits cytosolic leucine aminopeptidase, microsomal aminopeptidase M and bacterial leucine aminopeptidase, human serum aminopeptidase A (AP-A), aminopeptidase N (AP-N), tyrosine aminopeptidase, but not of aminopeptidase B (AP-B). Amastatin is without effect on trypsin, papain, chymotrypsin, elastase, pepsin, or thermolysin.Inhibits completely the Suc-Ala-Ala-Pro-Leu-pNA amidolytic enzyme. Slightly inhibits the formation of angiotensin III (Ang III) from Ang II through AP-A, but significantly increases the potency of angiotensin III and des(Asp1)angiotensin I. Moderate inhibitor of mitochondrial intermediate peptidase (MIP). Weak inhibitor of simian immunodeficiency virus protease (SIV-PR).
  • Purity
    >98%
  • Our products in action

Properties

  • Molecular Weight
    511.1
  • Chemical structure
    Amastatin hydrochloride [100938-10-1]
  • CAS Number
    100938-10-1
  • InChiKey
    GBDUPCKQTDKNLS-PORDUOSCSA-N
  • Appearance
    White to off-white powder

Storing and Using Your Product

  • Storage instructions
    +4°C
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Reviews & Product Guides