AMTB hydrochloride


Product overview

  • Name
    AMTB hydrochloride
  • Short description
    TRPM8 channel blocker
  • Biological description
    TRPM8 channel blocker (pIC50 = 6.23). Exhibits selectivity for TRPM8 channels over TRPV1 and TRPV4 channels. Displays antiproliferative properties.
  • Biological action
  • Purity
  • Our products in action


  • Chemical name
    N-(3-Aminopropyl)-2-[(3-methylpheny l)methoxy]-N-(2-thienylmethyl)benzamide hydrochloride
  • Molecular Weight
  • Chemical structure
    AMTB hydrochloride  [926023-82-7]
  • Molecular Formula
  • CAS Number
  • PubChem identifier
  • InChi
  • InChiKey

Storing and Using Your Product

  • Storage instructions
    Room temperature (desiccate)
  • Solubility overview
    Soluble in water (100mM) and in DMSO (100mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for AMTB hydrochloride

  • TRPM8 ion channels differentially modulate proliferation and cell cycle distribution of normal and cancer prostate cells.

    Valero ML et al (2012) PLoS One 7(12) : e51825.
    PubMedID: 23251635
  • AMTB, a TRPM8 channel blocker: evidence in rats for activity in overactive bladder and painful bladder syndrome.

    Lashinger ES et al (2008) Am J Physiol Renal Physiol 295(3) : F803-10.
    PubMedID: 18562636
  • Human TRPM8 and TRPA1 pain channels, including a gene variant with increased sensitivity to agonists (TRPA1 R797T), exhibit differential regulation by SRC-tyrosine kinase inhibitor.

    Morgan K et al (2014) Biosci Rep 34(4) :
    PubMedID: 24975826

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