Anacardic acid

(HB1380)

Pack	Price	Qty
5mg	$48
10mg	$75

(HB1380)

Data

Product overview

Name
Anacardic acid
Short description
Non-competitive HAT inhibitor
Biological description
Non-competitive histone acetyltransferase (HAT) inhibitor. Inhibits p300/CBP and p300-associated factor HAT actions (IC₅₀ values are 5 and 8.5 µM respectively). Also inhibits NF-κB, induces ER stress and autophagy. Shows anti-cancer and anti-inflammatory actions.
Alternative names
AA
Biological action
Inhibitor
Purity
>97%
Citations
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Storage instructions
-20°C
Solubility overview
soluble in DMSO (100mM) or ethanol (50mM)
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Small molecule modulators of histone acetyltransferase p300.
Balasubramanyam K et al (2003) J Biol Chem 278(21) : 19134-40.
PubMedID: 12624111
Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone acetyltransferase, suppresses expression of nuclear factor-kappaB-regulated gene products involved in cell survival, proliferation, invasion, and inflammation through inhibition of the i
Sung B et al (2008) Blood 111(10) : 4880-91.
PubMedID: 18349320
Induction of the endoplasmic reticulum stress and autophagy in human lung carcinoma A549 cells by anacardic acid.
Seong YA et al (2014) Cell Biochem Biophys 68(2) : 369-77.
PubMedID: 23955513

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