Anacardic acid

(HB1380)

Product overview

  • Name
    Anacardic acid
  • Short description
    Non-competitive HAT inhibitor
  • Biological description
    Non-competitive histone acetyltransferase (HAT) inhibitor. Inhibits p300/CBP and p300-associated factor HAT actions (IC50 values are 5 and 8.5 µM respectively). Also inhibits NF-κB, induces ER stress and autophagy. Shows anti-cancer and anti-inflammatory actions.
  • Alternative names
    AA
  • Biological action
    Inhibitor
  • Purity
    >97%
  • Our products in action

Properties

  • Chemical name
    2-Hydroxy-6-pentadecylbenzoic acid
  • Molecular Weight
    348.52
  • Chemical structure
    Anacardic acid  [16611-84-0]
  • Molecular Formula
    C22H36O3
  • CAS Number
    16611-84-0

Storing and Using Your Product

  • Storage instructions
    -20°C
  • Solubility overview
    soluble in DMSO (100mM) or ethanol (50mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Anacardic acid

  • Small molecule modulators of histone acetyltransferase p300.

    Balasubramanyam K et al (2003) J Biol Chem 278(21) : 19134-40.
    PubMedID: 12624111
  • Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone acetyltransferase, suppresses expression of nuclear factor-kappaB-regulated gene products involved in cell survival, proliferation, invasion, and inflammation through inhibition of the i

    Sung B et al (2008) Blood 111(10) : 4880-91.
    PubMedID: 18349320
  • Induction of the endoplasmic reticulum stress and autophagy in human lung carcinoma A549 cells by anacardic acid.

    Seong YA et al (2014) Cell Biochem Biophys 68(2) : 369-77.
    PubMedID: 23955513

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