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Data

Product overview

  • Name
    Aniracetam
  • Short description
    Nootrophic AMPA receptor positive allosteric modulator
  • Biological description
    Nootrophic AMPA receptor positive allosteric modulator, reduces glutamate receptor desensitisation and AMPA receptor deactivation. Shows anxiolytic properties.
  • Biological action
    PAM
  • Purity
    >98%
  • Citations

Properties

  • Chemical name
    1-(4-Methoxybenzoyl)-2-pyrrolidinone
  • Molecular Weight
    219.24
  • Chemical structure
    Aniracetam  [72432-10-1]
  • Molecular Formula
    C12H13NO3
  • CAS Number
    72432-10-1
  • PubChem identifier
    2196
  • SMILES
    O=C2CCCN2C(=O)c1ccc(OC)cc1
  • InChi
    InChI=1S/C12H13NO3/c1-16-10-6-4-9(5-7-10)12(15)13-8-2-3-11(13)14/h4-7H,2-3,8H2,1H3
  • InChiKey
    ZXNRTKGTQJPIJK-UHFFFAOYSA-N
  • MDL number
    MFCD00153767
  • Appearance
    White solid

Storing and Using Your Product

  • Storage instructions
    Room temperature
  • Solubility overview
    Soluble in ethanol (25mM), and in DMSO (100mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Aniracetam

  • Anxiolytic effects of aniracetam in three different mouse models of anxiety and the underlying mechanism.

    Nakamura K et al (2001) Eur J Pharmacol 420(1) : 33-43.
    PubMedID: 11412837
  • Aniracetam reduces glutamate receptor desensitization and slows the decay of fast excitatory synaptic currents in the hippocampus.

    Isaacson JS et al (1991) Proc Natl Acad Sci U S A 88(23) : 10936-40.
    PubMedID: 1660156
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