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Product overview

  • Name
  • Short description
    Potent HDAC inhibitor
  • Biological description
    Potent histone deacetylase (HDAC) inhibitor (IC50 = 5 nM). Shows anti-protozoal, anti-angiogenic, anti-proliferative and anti-cancer actions.
  • Biological action
  • Purity
  • Citations


  • Chemical name
    Cyclo[(2S)-2-Amino-8-oxodecanoyl-1- methoxy-L-tryptophyl-L-isoleucyl-(2R)-2-piperidine carbonyl]
  • Molecular Weight
  • Chemical structure
    Apicidin  [183506-66-3]
  • Molecular Formula
  • CAS Number

Storing and Using Your Product

  • Storage instructions
  • Solubility overview
    soluble in DMSO (2mM) or ethanol (2mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Apicidin

  • Apicidin, a histone deacetylase inhibitor, inhibits proliferation of tumor cells via induction of p21WAF1/Cip1 and gelsolin.

    Han JW et al (2000) Cancer Res 60(21) : 6068-74.
    PubMedID: 11085529
  • Apicidin: a novel antiprotozoal agent that inhibits parasite histone deacetylase.

    Darkin-Rattray SJ et al (1996) Proc Natl Acad Sci U S A 93(23) : 13143-7.
    PubMedID: 8917558
  • Apicidin is a histone deacetylase inhibitor with anti-invasive and anti-angiogenic potentials.

    Kim SH et al (2004) Biochem Biophys Res Commun 315(4) : 964-70.
    PubMedID: 14985106
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