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Product overview

  • Name
  • Short description
    PKC inhibitor
  • Biological description
    Protein kinase C (PKC) inhibitor that competes with ATP (IC50 = 30 µM for protein kinase CK2). Promotes cell cycle arrest and apoptosis. Displays antioxidant, anticarcinogenic and anti-inflammatory properties. A naturally occurring plant flavone.
  • Biological action
  • Purity
  • Citations


  • Chemical name
  • Molecular Weight
  • Chemical structure
    Apigenin  [520-36-5]
  • Molecular Formula
  • CAS Number
  • PubChem identifier

Storing and Using Your Product

  • Storage instructions
    Store at +4°C
  • Solubility overview
    soluble in DMSO (27mg/ml) or KOH (50mg/ml, 1M KOH)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Apigenin

  • Apigenin and cancer chemoprevention: progress, potential and promise (review).

    Patel D et al (2007) Int J Oncol 30(1) : 233-45.
    PubMedID: 17143534
  • Molecular targets for apigenin-induced cell cycle arrest and apoptosis in prostate cancer cell xenograft.

    Shukla S et al (2006) Mol Cancer Ther 5(4) : 843-52.
    PubMedID: 16648554
  • Suppression of protein kinase C and nuclear oncogene expression as possible molecular mechanisms of cancer chemoprevention by apigenin and curcumin.

    Lin JK et al (1997) J Cell Biochem Suppl 28-29 : 39-48.
    PubMedID: 9589348
  • Inhibition of protein kinase CK2 prevents the progression of glomerulonephritis.

    Yamada M et al (2005) Proc Natl Acad Sci U S A 102(21) : 7736-41.
    PubMedID: 15897466
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