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Product overview

  • Name
  • Short description
    Plasmodium falciparum SERCA orthologue inhibitor
  • Biological description
    Plasmodium falciparum SERCA orthologue (PfATP6) inhibitor (Ki = 150 nM). Thought to generate cytotoxic C-radicals. Shows anti-malarial, anti-proliferative and anti-neoplastic actions.
  • Biological action
  • Purity
  • Citations


  • Chemical name
    (3R,5aS,6R,8aS,9R,12S,12aR)-Octahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1, 2-benzodioxepin-10(3H)-one
  • Molecular Weight
  • Chemical structure
    Artemisinin  [63968-64-9]
  • Molecular Formula
  • CAS Number

Storing and Using Your Product

  • Storage instructions
  • Solubility overview
    soluble in DMSO (100mM) or ethanol (75mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Artemisinin

  • Artemisinins target the SERCA of Plasmodium falciparum.

    Eckstein-Ludwig U et al (2003) Nature 424(6951) : 957-61.
    PubMedID: 12931192
  • Artemisinin inhibits neuroblastoma proliferation through activation of AHP-activated protein kinase (AMPK) signaling.

    Tan WQ et al (2014) Pharmazie 69(6) : 468-72.
    PubMedID: 24974584
  • Considerations on the mechanism of action of artemisinin antimalarials: part 1--the 'carbon radical' and 'heme' hypotheses.

    Haynes RK et al (2013) Infect Disord Drug Targets 13(4) : 217-77.
    PubMedID: 24304352
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