AZM 475271

(HB1322)

Product overview

  • Name
    AZM 475271
  • Short description
    Src tyrosine kinase inhibitor
  • Biological description
    Src tyrosine kinase inhibitor. Shows anti-proliferative, apoptotic, anti-angiogenic, anti-lymphangiogenic and antimetastatic actions against cancer.
  • Biological action
    Inhibitor
  • Purity
    >99%
  • Our products in action

Properties

  • Chemical name
    N-(2-Chloro-5-methoxyphenyl)-6-methoxy
  • Molecular Weight
    442.94
  • Molecular Formula
    C23H27ClN4O3
  • CAS Number
    476159-98-5

Storing and Using Your Product

  • Storage instructions
    room temperature
  • Solubility overview
    soluble in DMSO (100mM)

References for AZM 475271

  • Inhibition of SRC tyrosine kinase as treatment for human pancreatic cancer growing orthotopically in nude mice.

    Yezhelyev MV et al (2004) Clin Cancer Res 10(23) : 8028-36.
    PubMedID: 15585638
  • Effect of Src kinase inhibition on metastasis and tumor angiogenesis in human pancreatic cancer.

    Ischenko I et al (2007) Angiogenesis 10(3) : 167-82.
    PubMedID: 17486419
  • Src tyrosine kinase inhibition suppresses lymphangiogenesis in vitro and in vivo.

    Ischenko I et al (2010) Curr Cancer Drug Targets 10(5) : 546-53.
    PubMedID: 20370688

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