Bakuchiol

(HB0129)

Product overview

  • Name
    Bakuchiol
  • Short description
    PTB1B inhibitor
  • Biological description
    Protein tyrosine phosphatase 1B (PTB1B) inhibitor (IC50 = 20.8 µM). Inhibits mitochondrial lipid peroxidation. Shows antibacterial, antioxidant and antitumor actions.
  • Biological action
    Inhibitor
  • Purity
    >97%
  • Citations

Properties

  • Chemical name
    4-(3-Ethenyl-3,7-dimethyl-1,6-octadienyl)phenol
  • Molecular Weight
    256.4
  • Chemical structure
    Bakuchiol  [10309-37-2]
  • Molecular Formula
    C18H24O
  • CAS Number
    10309-37-2
  • PubChem identifier
    5468522
  • SMILES
    CC(=CCCC(C)(C=C)C=CC1=CC=C(C=C1)O)C

Storing and Using Your Product

  • Solubility overview
    soluble in DMSO or ethanol
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Bakuchiol

  • In vitro protein tyrosine phosphatase 1B inhibitory phenols from the seeds of Psoralea corylifolia.

    Kim YC et al (2005) Planta Med 71(1) : 87-9.
    PubMedID: 15678382
  • Inhibition of mitochondrial lipid peroxidation by Bakuchiol, a meroterpene from Psoralea corylifolia.

    Haraguchi H et al (2000) Planta Med 66(6) : 569-71.
    PubMedID: 10985089
  • Anti-tumor effects of bakuchiol, an analogue of resveratrol, on human lung adenocarcinoma A549 cell line.

    Chen Z et al (2010) Eur J Pharmacol 643(2-3) : 170-9.
    PubMedID: 20599920
  • Bakuchiol, an antibacterial component of Psoralidium tenuiflorum.

    Hsu PJ et al (2009) Nat Prod Res 23(8) : 781-8.
    PubMedID: 19418361

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