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Biological Data

Biological description Protein tyrosine phosphatase 1B (PTB1B) inhibitor (IC50 = 20.8 µM). Inhibits mitochondrial lipid peroxidation. Shows antibacterial, antioxidant and antitumor actions.

Solubility & Handling

Solubility overview Soluble in DMSO or ethanol
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Chemical Data

Purity >97%
Chemical name 4-(3-Ethenyl-3,7-dimethyl-1,6-octadienyl)phenol
Molecular Weight 256.4
Chemical structure Bakuchiol  [10309-37-2] Chemical Structure
Molecular Formula C18H24O
CAS Number 10309-37-2
PubChem identifier 5468522
SMILES CC(=CCCC(C)(C=C)C=CC1=CC=C(C=C1)O)C

References for Bakuchiol

References are publications that support the biological activity of the product
  • Anti-tumor effects of bakuchiol, an analogue of resveratrol, on human lung adenocarcinoma A549 cell line.

    Chen Z et al (2010) Eur J Pharmacol 643(2-3) : 170-9.
  • Bakuchiol, an antibacterial component of Psoralidium tenuiflorum.

    Hsu PJ et al (2009) Nat Prod Res 23(8) : 781-8.
  • In vitro protein tyrosine phosphatase 1B inhibitory phenols from the seeds of Psoralea corylifolia.

    Kim YC et al (2005) Planta Med 71(1) : 87-9.
  • Inhibition of mitochondrial lipid peroxidation by Bakuchiol, a meroterpene from Psoralea corylifolia.

    Haraguchi H et al (2000) Planta Med 66(6) : 569-71.

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