Bisindolylmaleimide IX methansulfonate

(HB2958)
Technical documents: Datasheet

Product overview

Name Bisindolylmaleimide IX methansulfonate
Alternative names Bisindolylmaleimide IX
Purity >98%
Description Selective, cell permeable PKC inhibitor
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Biological Data

Biological description Selective and cell permeable protein kinase C (PKC) inhibitor. Inhibits the stimulation of insulin secretion by glucose. Inhibits T cell activation. Apoptosis inducer. Potent glycogen synthase kinase-3 (GSK-3) inhibitor. Transcription inhibitor. Induces TNF receptor family-mediated cell death. Pim-1 kinase inhibitor. Antitumor compound.

Solubility & Handling

Storage instructions +4°C
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >98%
Molecular Weight 553.7
Molecular Formula C25H23N5O2S.CH3SO3H
CAS Number 138489-18-6
PubChem identifier 11628205
SMILES CS(O)(=O)=O.CN1C=C(C2=CC=CC=C12)C1=C(C(=O)NC1=O)C1=CN(CCCSC(N)=N)C2=CC=CC=C12
InChiKey SAWVGDJBSPLRRB-UHFFFAOYSA-N
Appearance Red solid