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An alternative to CNO? Water soluble Compound 21 (DREADD agonist 21)

An alternative to CNO? Water soluble Compound 21 (DREADD agonist 21)
By Sam Roome 7 months ago 43045 Views 1 comment

Do you work with DREADDs? We have launched water soluble Compound 21 (DREADD agonist 21), a highly potent hM3Dq DREADD agonist. This product can be used as an alternative to clozapine N-oxide (water soluble) - it has a similar in vivo potency, but unlike CNO, it is less likely to metabolize to clozapine. Together with the water soluble hydrochloride salt, we have also launched the free base version of DREADD agonist 21.

#dreadd Posted in: Lab support
Ali 7 months ago at 10:00
That's interesting - I've literally just read that paper by Gomez and others...