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Novel water-soluble, potent DREADD ligands, licensed from the NIH

By Sam Roome 12 days ago 1138 Views No comments

We are delighted to announce that we have launched two novel water-soluble hM3Dq & hM4Di ligands – JHU37160 dihydrochloride and JHU37152 dihydrochloride. These are exciting tools for scientists studying GPCR and DREADD signalling. Hello Bio has been granted a licence from the National Institutes of Health to manufacture these novel tools and make them commercially available for the first time to life scientists worldwide. Find out more...

The Life Scientists’ Guide to Wellbeing

By Sam Roome 1 month ago 3020 Views No comments

We know you love what you do, and we understand how hard life scientists work – and that it’s often out of choice, rather than necessity. But working hard doesn’t mean you have to neglect yourself. Read our guide to find out what wellbeing actually is, and how we scientists can look after ourselves better, and support our colleagues to do the same.

The Most Common PhD Problems & How to Get Past Them

By Sam Roome 1 month ago 17006 Views No comments

When you are starting out on your PhD, we believe you need all the help you can get! As a starting place, check out this advice from our fantastic guest blogger Lizzie Mann on how to deal with some common problems that you may encounter...

How Early Career Life Scientists Can Use Social Media Effectively

By Sam Roome 1 month ago 3116 Views No comments

It’s fair to assume that social media probably isn’t going to go away any time soon. Which means whether you love it or hate it, it’s a good idea to start thinking about how you can use it to support your work and raise your profile – especially if you’re an early career researcher. Read this hugely valuable advice by our guest blogger Dr Emma Yhnell...

The Life Scientists’ Guide For New PhD Students

By Sam Roome 2 months ago 35340 Views No comments

As scientists ourselves, we know how daunting it feels when you embark upon on your first PhD. Especially right at the beginning, when everything can feel totally new and overwhelming.

To show you just how much support there is for you in the life science community from your peers (and from us!) we’ve put together The Life Scientists’ Guide for New PhD Students. Here, you’ll find the fantastic advice our fellow scientists have shared with us, as well as a few tips from our personal experience.

Stability of DREADD Ligands in Solution - a Review

By Sam Roome 3 months ago 356 Views 1 comment

Check out our new technical review: Stability of DREADD ligands in solution. Find out all you need to know about how to handle, store and use commonly used water-soluble DREADD ligands (such as Clozapine N-oxide dihydrochloride, and Compound 21 dihydrochloride) - and discover brand new data on the stability of these important tools.

Review on Neural Stem Cells & Small Molecules

By Sam Roome 3 months ago 384 Views No comments

Check out our new mini-review on Neural Stem Cells & Small Molecules - it includes descriptions of the small molecules commonly used in neural stem cell research, and the signaling pathways that they target...

The Big Life Scientist Survey: Here’s What You Told Us

By Sam Roome 5 months ago 2061 Views 2 comments

The results of The Big Life Scientist Survey are in!

Thank you so much to all of you 222 life scientists from around the world who took the time to answer our questions and helped spread the word about the survey.

We asked the life sciences community a range of questions around funding, study replication, lifestyle, equal opportunities and diversity with some eye opening results...

Synaptic Plasticity Review

By Sam Roome 5 months ago 522 Views No comments

Check out our new mini-review on synaptic plasticity - including types and mechanisms of short-term and long-term synaptic plasticity, plus pharmacological manipulation, useful tables, diagrams and more...

The Big Life Scientist Survey

By Sam Roome 7 months ago 1722 Views No comments

Scientists, we want to hear your views in The Big Life Scientist Survey!

The aim of The Big Life Scientist Survey is to highlight the biggest challenges life scientists are facing today around funding, pressure, publication and more. It’ll only take you five minutes to complete, it's completely anonymous, and at the end you can have the option of entering our prize draw to win $500 of Hello Bio vouchers too.