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First photoactive mGlu5 receptor NAM analgesic

First photoactive mGlu5 receptor NAM analgesic
By Sam Roome 11 months ago 51896 Views No comments

We have an exclusive for you: JF-NP-26 (Caged-Raseglurant) is the first photoactive mGlu5 negative allosteric modulator that shows analgesic effects in vivo. Systemic administration, followed by local LED-based illumination, induces JF-NP-26-mediated light-dependent analgesia both in neuropathic and in inflammatory pain models. Brought to you first by Hello Bio!