In my cart

You have no items in your shopping cart.

Data

Product overview

  • Name
    BLZ-945
  • Short description
    Potent, selective colony stimulating factor 1 receptor (CSF-1R) inhibitor
  • Biological description
    Orally active, potent and selective colony stimulating factor 1 receptor (CSF-1R) inhibitor. More than 1000-fold selective against its closest receptor tyrosine kinase homologs c-KIT and platelet-derived growth factor receptor beta (PDGFRbeta). Selective against more than 200 additional kinases.
  • Purity
    >95%
  • Citations

Properties

  • Chemical name
    4-[[2-[[(1R,2R)-2-hydroxycyclohexyl]amino]-6-benzothiazolyl]oxy]-N-methyl-2-pyridinecarboxamide
  • Molecular Weight
    398.5
  • Chemical structure
    BLZ-945 [953769-46-5]
  • Molecular Formula
    C20H22N4O3S
  • CAS Number
    953769-46-5
  • PubChem identifier
    46184986
  • SMILES
    CNC(=O)C1=NC=CC(=C1)OC2=CC3=C(C=C2)N=C(S3)N[C@@H]4CCCC[C@H]4O
  • InChi
    InChI=1S/C20H22N4O3S/c1-21-19(26)16-10-13(8-9-22-16)27-12-6-7-15-18(11-12)28-20(24-15)23-14-4-2-3-5-17(14)25/h6-11,14,17,25H,2-5H2,1H3,(H,21,26)(H,23,24)/t14-,17-/m1/s1
  • InChiKey
    ADZBMFGQQWPHMJ-RHSMWYFYSA-N
  • MDL number
    MFCD28142668
  • Appearance
    Pale yellow solid

Storing and Using Your Product

  • Storage instructions
    +4°C
  • Solubility overview
    Soluble in DMSO
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Support & Resources

Reviews & Product Guides