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Borrelidin

(HB3810)
Data

Product overview

  • Name
    Borrelidin
  • Short description
    Antibiotic. Threonyl-tRNA synthetase (THrRS) inhibitor.
  • Biological description
    Antibiotic. Threonyl-tRNA synthetase (THrRS) inhibitor. Cyclin-dependent kinase (CDK) inhibitor. Induces the collapse of formed capillary tubes in a dose-dependent fashion. In HUVECs, the capillary tube collapsing activity is mediated by the activation of caspases-3 and -8 and apoptosis induction. Shows anticancer, antiangiogenic and antiviral activity.
  • Purity
    >98%
  • Citations

Properties

  • Chemical name
    (1R,2R)-2-[(2S,4E,6Z,8R,9S,11R,13S,15S,16S)-7-Cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl]cyclopentanecarboxylic acid
  • Molecular Weight
    489.6
  • Chemical structure
    Borrelidin [7184-60-3]
  • Molecular Formula
    C28H43NO6
  • CAS Number
    7184-60-3
  • PubChem identifier
    6436801
  • SMILES
    O[C@@H](C1)[C@@H](C)C[C@@H](C)C[C@@H](C)C[C@H](C)[C@@H](O)\C(C#N)=C/C=C/C[C@]([C@]2([H])CCC[C@H]2C(O)=O)([H])OC1=O
  • Source
    Streptomyces sp.
  • InChi
    InChI=1S/C28H43NO6/c1-17-12-18(2)14-20(4)27(32)21(16-29)8-5-6-11-25(22-9-7-10-23(22)28(33)34)35-26(31)15-24(30)19(3)13-17/h5-6,8,17-20,22-25,27,30,32H,7,9-15H2,1-4H3,(H,33,34)/b6-5+,21-8-/t17-,18+,19-,20-,22+,23+,24-,25-,27+/m0/s1
  • InChiKey
    OJCKRNPLOZHAOU-TVHKGLGPSA-N
  • MDL number
    MFCD01740784
  • Appearance
    White to off-white powder

Storing and Using Your Product

  • Storage instructions
    +4°C
  • Solubility overview
    Soluble in DMSO
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
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