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Product overview

  • Name
  • Short description
    Potent protein PTP inhibitor
  • Biological description
    Potent protein phosphotyrosine phosphatase (PTP) inhibitor (IC50 values are 18 and 164 nM for PTP-β and PTP-1B respectively). Also inhibits phosphatase and tensin homologue (PTEN) (IC50 = 18 nM). Displays insulin-mimetic properties.
  • Biological action
  • Purity
  • Citations


  • Chemical name
  • Molecular Weight
  • Chemical structure
  • Molecular Formula
  • CAS Number

Storing and Using Your Product

  • Storage instructions
  • Solubility overview
    soluble in water
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for bpV(bipy)

  • Inhibition Effects of Some Bioactive Peroxovanadium Complexes on the Tyrosine Phosphatase.

    Zhou XW et al (2000) Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) 32(2) : 133-138.
    PubMedID: 12098789
  • Peroxovanadium compounds. A new class of potent phosphotyrosine phosphatase inhibitors which are insulin mimetics.

    Posner BI et al (1994) J Biol Chem 269(6) : 4596-604.
    PubMedID: 8308031
  • Bisperoxovanadium compounds are potent PTEN inhibitors.

    Schmid AC et al (2004) FEBS Lett 566(1-3) : 35-8.
    PubMedID: 15147864
  • Early signaling events triggered by peroxovanadium [bpV(phen)] are insulin receptor kinase (IRK)-dependent: specificity of inhibition of IRK-associated protein tyrosine phosphatase(s) by bpV(phen).

    Band CJ et al (1997) Mol Endocrinol 11(13) : 1899-910.
    PubMedID: 9415395
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