Thymidine analog. Widely used to identify proliferating cells.
Thymidine analog which is incorporated into DNA during DNA replication (during S-phase of cell cycle).
BrdU is used to identify proliferating cells. Labels cell lines and primary cell cultures in vitro and also cells in vivo.
Widely used to study adult neurogenesis. Can be used in combination with neuron specific markers such as NeuN to identify newly formed neurons.
Frequently used to label and fate-map dividing cells in neural stem cell biology.
5-BrdU, 5-bromo-2'-deoxyuridine, Broxuridine
Dyes & stains
Storing and Using Your Product
Soluble in water (50mM) and in DMSO (100mM)
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
References for BrdU (5-Bromo-2′-deoxyuridine)
Pharmacological evaluation of intravenous delivery of 5-bromodeoxyuridine to patients with brain tumors.Russo A et al (1984) Cancer Res 44(4) : 1702-5.PubMedID: 6704976
Neurogenesis in the adult human hippocampus.Eriksson PS et al (1998) Nat Med 4(11) : 1313-7.PubMedID: 9809557
The dark side of BrdU in neural stem cell biology: detrimental effects on cell cycle, differentiation and survival.Lehner B et al (2011) Cell Tissue Res 345(3) : 313-28.PubMedID: 21837406
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