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Brilliant Blue G


Product overview

  • Name
    Brilliant Blue G
  • Short description
    Non-competitive P2X7 antagonist. Protein-binding dye.
  • Alternative names
    Acid blue 90; Coomassie Brilliant Blue G; NSC 328382; CBBG
  • Biological description
    Non-competitive P2X7 antagonist (IC50 values are 10 and 200 nM at rat and human P2X7 respectively). Displays neuroprotective and anti-inflammatory properties. Also a protein binding dye causing a colour change from red to blue.
  • Biological action
    Dyes & stains
  • Citations


  • Chemical name
    Coomassie Brilliant Blue G (CBBG)
  • Molecular Weight
  • Chemical structure
    Brilliant Blue G  [6104-58-1]
  • Molecular Formula
  • CAS Number
  • PubChem identifier

Storing and Using Your Product

  • Storage instructions
    room temperature
  • Solubility overview
    soluble in water (40mg/ml, at 20 oC) or methanol
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Brilliant Blue G

  • Block of purinergic P2X(7) receptor is neuroprotective in an animal model of Alzheimer's disease.

    Ryu JK et al (2008) Neuroreport 19(17) : 1715-9.
    PubMedID: 18852683
  • Brilliant blue G selectively blocks ATP-gated rat P2X(7) receptors.

    Jiang LH et al (2000) Mol Pharmacol 58(1) : 82-8.
    PubMedID: 10860929
  • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

    Bradford MM (1976) Anal Biochem 72 : 248-54.
    PubMedID: 942051
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