Product overview

Name Brilliant Blue G
Alternative names Acid blue 90; Coomassie Brilliant Blue G; NSC 328382; CBBG
Biological description Non-competitive P2X7 antagonist (IC50 values are 10 and 200 nM at rat and human P2X7 respectively). Displays neuroprotective and anti-inflammatory properties. Also a protein binding dye causing a colour change from red to blue.
Description Non-competitive P2X7 antagonist. Protein-binding dye.
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Images

Brilliant Blue G product vial image | Hello Bio

Solubility & Handling

Storage instructions Room temperature
Solubility overview Soluble in water (40mg/ml, at 20°C) or methanol
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Chemical name Coomassie Brilliant Blue G (CBBG)
Molecular Weight 854.02
Chemical structure Brilliant Blue G  [6104-58-1] Chemical Structure
Molecular Formula C47H48N3NaO7S2
CAS Number 6104-58-1
PubChem identifier 6324599
SMILES CCN(CC1=CC(=CC=C1)S(=O)(=O)[O-])C2=CC(=C(C=C2)/C(=C/3\C=CC(=[N+](CC)CC4=CC(=CC=C4)S(=O)(=O)[O-])C=C3C)/C5=CC=C(C=C5)NC6=CC=C(C=C6)OCC)C.[Na+]

References for Brilliant Blue G

References are publications that support the biological activity of the product
  • Block of purinergic P2X(7) receptor is neuroprotective in an animal model of Alzheimer's disease.

    Ryu JK et al (2008) Neuroreport 19(17) : 1715-9.
  • Brilliant blue G selectively blocks ATP-gated rat P2X(7) receptors.

    Jiang LH et al (2000) Mol Pharmacol 58(1) : 82-8.
  • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

    Bradford MM (1976) Anal Biochem 72 : 248-54.

3 Item(s)