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Bromocriptine mesylate

(HB1813)
Data

Product overview

  • Name
    Bromocriptine mesylate
  • Short description
    Potent, selective D2-like receptor agonist
  • Biological description
    Potent, selective D2-like receptor agonist (Ki values are 5.3, 7.4, 454 and 645 nM at D2, D3, D5 and D1 receptors respectively). Prototypic antiparkinsonian agent. Active in vivo.
  • Biological action
    Agonist
  • Purity
    >98%
  • Citations

Properties

  • Chemical name
    (5'a)-2-Bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)ergotaman-3',6',18-trione mesylate
  • Molecular Weight
    750.7
  • Chemical structure
    Bromocriptine mesylate  [22260-51-1]
  • Molecular Formula
    C32H40BrN5O5.CH3SO3H
  • CAS Number
    22260-51-1

Storing and Using Your Product

  • Storage instructions
    room temperature
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Bromocriptine mesylate

  • Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1.

    Sunahara RK et al (1991) Nature 350(6319) : 614-9.
    PubMedID: 1826762
  • Differential involvement of D1 and D2 dopamine receptors in L-DOPA-induced angiogenic activity in a rat model of Parkinson's disease.

    Lindgren HS et al (2009) Neuropsychopharmacology 34(12) : 2477-88.
    PubMedID: 19606087
  • The D3 dopamine receptor: neurobiology and potential clinical relevance.

    Levant B (1997) Pharmacol Rev 49(3) : 231-52.
    PubMedID: 9311022
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