In my cart

You have no items in your shopping cart.

Calphostin C


Product overview

  • Name
    Calphostin C
  • Short description
    Potent, selective PKC inhibitor. Also antagonizes the Tcf/β-catenin complex
  • Biological description
    Potent and selective photo-activated PKC inhibitor (IC50 = 50 nM). Antagonizes the Tcf/β-catenin complex. Inhibits glioma tumour cell proliferation and protects the myocardium against ischemic injury.
  • Alternative names
    UCN 1028C|PKF 115-584
  • Biological action
  • Purity
  • Citations


  • Chemical name
    (1R)-2-[12-[(2R)-2-(Benzoyloxy)propyl]-3,10-dihydro-4,9-dihydroxy-2,6,7,11-tetramethoxy-3,10-dioxo-1-perylenyl]-1-methylethylcarbonic acid 4-hydroxyphenyl ester
  • Molecular Weight
  • Chemical structure
    Calphostin C  [121263-19-2]
  • Molecular Formula
  • CAS Number
  • PubChem identifier

Storing and Using Your Product

  • Storage instructions
    +4°C (desiccate)
  • Solubility overview
    soluble in DMSO or ethanol
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Calphostin C

  • The effect of calphostin C, a potent photodependent protein kinase C inhibitor, on the proliferation of glioma cells in vitro.

    Pollack IF et al (1997) J Neurooncol 31(3) : 255-66.
    PubMedID: 9049854
  • The role of protein kinase in C ischemic/reperfused preconditioned isolated rat hearts.

    Tosaki A et al (1996) J Cardiovasc Pharmacol 28(5) : 723-31.
    PubMedID: 8945687
  • In vitro effects of a small-molecule antagonist of the Tcf/β-catenin complex on endometrial and endometriotic cells of patients with endometriosis.

    Matsuzaki S et al (2013) PLoS One 8(4) : e61690.
    PubMedID: 23626717
Support & Resources

Reviews & Product Guides