cAMPS-Sp triethylammonium salt

(HB0566)
Technical documents: Datasheet

Product overview

Name cAMPS-Sp triethylammonium salt
Purity >98%
Description Potent, specific cAMP-dependent protein kinases activator. Cell-permeable.
Write Your Own Review
You're reviewing:cAMPS-Sp triethylammonium salt
Rate this item:

Biological Data

Biological description Potent, specific cAMP-dependent protein kinases activator. Cell-permeable. Unique tool for studying cAMP-dependent signaling due to it cell permeability and complete resistance to cyclic nucleotide phosphodiesterases. Shows higher resistance against cyclic nucleotide-dependent phosphodiesterases compared to dibutyryl-cAMP or 8-Br-cAMP. No metabolic side effects are shown.

Solubility & Handling

Storage instructions -20° (desiccate)
Solubility overview Soluble in water (25mg/ml) or DMSO, DMF or methanol
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

=
x
x
More Info

Dilution

x
=
x
More Info

Chemical Data

Purity >98%
Chemical name (S)-Adenosine, cyclic 3',5'-(hydrogenphosphorothioate) triethylammonium
Molecular Weight 446.5
Molecular Formula C10H11N5O5PS.C6H16N
CAS Number 93602-66-5
PubChem identifier 16072219
SMILES [H][C@@]([C@@](O[C@@H](N3C=NC4=C3N=CN=C4N)[C@@H]2O)([H])CO1)2O[P@]1([S-])=O.CC[NH+](CC)CC

References for cAMPS-Sp triethylammonium salt

References are publications that support the biological activity of the product
  • Probing the cyclic nucleotide binding sites of cAMP-dependent protein kinases I and II with analogs of adenosine 3',5'-cyclic phosphorothioates

    Dostmann et al (1990) J Biol Chem. 265(18) : 10484-91.
  • A kinetic study of interactions of (Rp)- and (Sp)-adenosine cyclic 3',5'-phosphorothioates with type II bovine cardiac muscle adenosine cyclic 3',5'-phosphate dependent protein kinase

    Brian et al (1982) Biochemistry 21(18) : 4371-6.

2 Item(s)