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(-)-Cannabidiol

(HB2785)
Data

Product overview

  • Name
    (-)-Cannabidiol
  • Short description
    Nonpsychoactive cannabinoid found in cannabis
  • Biological description
    Nonpsychoactive cannabinoid found in cannabis. Demonstrates low affinity for CB1 and CB2 receptors (Ki values are 4.35 and 2.86 μM respectively). Also acts as a GPR55 antagonist. Shows anxiolytic, anti psychotic, antidepressant and neuroprotective properties. Active in vivo,
  • Alternative names
    CBD
  • Biological action
    Agonist
  • Purity
    >98%
  • Citations

Properties

  • Chemical name
    2-[(1R,6R)-3-Methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-5-pentyl-1,3-benzenediol
  • Molecular Weight
    314.47
  • Chemical structure
    Cannabidiol CBD [13956-29-1]
  • Molecular Formula
    C21H30O2
  • CAS Number
    13956-29-1
  • PubChem identifier
    644019
  • SMILES
    CCCCCC1=CC(=C(C(=C1)O)[C@@H]2C=C(CC[C@H]2C(=C)C)C)O
  • InChi
    InChI=1S/C21H30O2/c1-5-6-7-8-16-12-19(22)21(20(23)13-16)18-11-15(4)9-10-17(18)14(2)3/h11-13,17-18,22-23H,2,5-10H2,1,3-4H3/t17-,18+/m0/s1
  • InChiKey
    QHMBSVQNZZTUGM-ZWKOTPCHSA-N
  • MDL number
    MFCD00869597

Storing and Using Your Product

  • Storage instructions
    -20°C
  • Solubility overview
    Soluble in ethanol (75 mM) and in DMSO (75 mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for (-)-Cannabidiol

  • The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: delta9-tetrahydrocannabinol, cannabidiol and delta9-tetrahydrocannabivarin.

    Pertwee (2008) Br J Pharmacol 153(2) : 199-215
    PubMedID: 17828291
  • Type 1 cannabinoid receptor ligands display functional selectivity in a cell culture model of striatal medium spiny projection neurons.

    Laprairie et al (2014) J Biol Chem 289(36) : 24845-62
    PubMedID: 25037227
  • The orphan receptor GPR55 is a novel cannabinoid receptor.

    Ryberg et al (2007) Br J Pharmacol 152(7) : 1092-101.
    PubMedID: 17876302
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