Product overview

Name Carboplatin
Alternative names NSC 241240, Paraplatin, JM 8
Purity >98%
Description Cisplatin analog. Blocks DNA replication and transcription.
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Biological Data

Biological description Potent platinum-based antineoplastic agent. Analog of cisplatin with reduced nephrotoxicity and higher stability. Antitumor agent. Forms inter- and intrastrand DNA adducts/crosslinks, consequently blocking DNA replication and transcription and inducing cell death. Interferes with cell division by mitosis. The damaged DNA elicits DNA repair mechanisms, which in turn activate apoptosis when repair is impossible. Apoptosis inducer. Enhances radiation-induced single-strand DNA breakage.

Solubility & Handling

Storage instructions +4°C
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Chemical Data

Purity >98%
Chemical name cis-Diammine(cyclobutane-1,1-dicarboxylate-O,O')platinum(II)
Molecular Weight 371.3
Chemical structure Carboplatin [41575-94-4] Chemical Structure
Molecular Formula C6H12N2O4Pt
CAS Number 41575-94-4
PubChem identifier 10339178
SMILES O=C(C21CCC2)O[Pt-2]([NH3+])([NH3+])OC1=O
InChiKey YAYRGNWWLMLWJE-UHFFFAOYSA-L
Appearance White to off-white powder