Carboxy-PTIO, potassium salt

(HB0169)

Product overview

  • Name
    Carboxy-PTIO, potassium salt
  • Short description
    NO scavenger
  • Biological description
    Nitric oxide (NO) scavenging free radical. Reacts with NO stoichiometrically. Reduces withdrawal-induced anxiety behaviours.
  • Purity
    >98%
  • Our products in action

Properties

  • Chemical name
    2-(4-Carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide potassium salt
  • Molecular Weight
    315.39
  • Chemical structure
    Carboxy-PTIO, potassium salt  [148819-94-7]
  • Molecular Formula
    C14H16KN2O4
  • CAS Number
    148819-94-7
  • PubChem identifier
    2733502
  • SMILES
    CC1(C([N+](=C(N1[O])C2=CC=C(C=C2)C(=O)[O-])[O-])(C)C)C.[K+]

Storing and Using Your Product

  • Solubility overview
    soluble in water (100mg/ml) or DMSO
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Carboxy-PTIO, potassium salt

  • Antagonistic action of imidazolineoxyl N-oxides against endothelium-derived relaxing factor/.NO through a radical reaction.

    Akaike T et al (1993) Biochemistry 32(3) : 827-32.
    PubMedID: 8422387
  • Vasodilator effect of carboxy-2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl in the coronary circulation: in vivo and in vitro studies.

    Tsunoda R et al (1994) Eur J Pharmacol 262(1-2) : 55-63.
    PubMedID: 7813579
  • Nitric oxide scavenging causes remodeling of the endoplasmic reticulum, Golgi apparatus and mitochondria in pulmonary arterial endothelial cells.

    Lee JE et al (2013) Nitric Oxide 33 : 64-73.
    PubMedID: 23770576
  • Effects of nitric oxide synthase inhibition in the dorsolateral periaqueductal gray matter on ethanol withdrawal-induced anxiety-like behavior in rats.

    Bonassoli VT et al (2013) Psychopharmacology (Berl) 228(3) : 487-98.
    PubMedID: 23494233

Reviews & Product Guides