Cesium Gluconate (Cs-Gluc)

(HB4822)

Product overview

  • Name
    Cesium Gluconate (Cs-Gluc)
  • Short description
    Potassium channel blocker. Component in cesium gluconate-based internal solutions used for patch clamp electrophysiology.
  • Biological description

    Cesium gluconate is used as a component in cesium gluconate-based internal (intracellular) solutions for patch clamp electrophysiology.


    Cesium blocks potassium (K+) channels and K+ currents to help provide a good space clamp.


    Cesium-gluconate based internal solutions are commonly used for voltage-clamp applications and are useful when studying EPSCs (excitatory postsynaptic currents) / IPSCs (inhibitory postsynaptic currents).


  • Alternative names
    CeGlu, Cs-Gluc, Cs-Gluconate, CsGluconate
  • Biological action
    Blocker
  • Customer comments

    We prepared a variety of Cesium Gluconate-based intracellular solutions to record excitatory synaptic currents from brain slices using whole-cell patch clamp. All solutions prepared using the Hello Bio Cesium Gluconate performed exactly as expected, saving us the time and trouble of synthesising the salt “in-house".

    Verified customer, the University of Dundee

  • Our products in action

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Properties

  • Chemical name
    D-Gluconic acid cesium salt
  • Molecular Weight
    328.05
  • Chemical structure
    Cesium gluconate
  • Molecular Formula
    C6H11CsO7
  • SMILES
    C([C@H]([C@H]([C@@H]([C@H](C(=O)[O-])O)O)O)O)O.[Cs+]
  • Source
    Synthetic
  • Appearance
    White solid

Storing and Using Your Product

  • Storage instructions
    +4°C
  • Solubility overview
    Soluble in water (200 mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Cesium Gluconate (Cs-Gluc)

  • Analysis of the effects of cesium ions on potassium channel currents in biological membranes.

    Clay and Shlesinger (1984) J Theor Biol 107(2) : 189-201
    PubMedID: 6325824
  • Voltage clamp studies on the effect of internal cesium ion on sodium and potassium currents in the squid giant axon.

    Adelman and Senft (1966) J Gen Physiol 50(2) : 279-93
    PubMedID: 11526829
  • An ion's view of the potassium channel. The structure of the permeation pathway as sensed by a variety of blocking ions.

    French and Shoukimas (1985) J Gen Physiol 85(5) : 669-98
    PubMedID: 2582077

Reviews & Product Guides

Reviews

  • Verified customer, The University of Dundee

    We prepared a variety of Cesium Gluconate-based intracellular solutions to record excitatory synaptic currents from brain slices using whole-cell patch clamp. All solutions prepared using the Hello Bio Cesium Gluconate performed exactly as expected, saving us the time and trouble of synthesising the salt “in-house".