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Product overview

  • Name
  • Short description
    Selective, non-competitive AMPA receptor antagonist
  • Biological description
    Selective and non-competitive AMPA receptor antagonist. Inhibits ERK1/2 pathway and acts as an antiproliferative agent. Also shows anticonvulsant actions.
  • Biological action
  • Purity
  • Citations


  • Chemical name
  • Molecular Weight
  • Chemical structure
    CFM-2  [178616-26-7]
  • Molecular Formula
  • CAS Number

Storing and Using Your Product

  • Storage instructions
    room temperature
  • Solubility overview
    soluble in DMSO (100mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for CFM-2

  • Effects of some AMPA receptor antagonists on the development of tolerance in epilepsy-prone rats and in pentylenetetrazole kindled rats.

    De Sarro G et al (1999) Eur J Pharmacol 368(2-3) : 149-59.
    PubMedID: 10193651
  • AMPA antagonists inhibit the extracellular signal regulated kinase pathway and suppress lung cancer growth.

    Stepulak A et al (2007) Cancer Biol Ther 6(12) : 1908-15.
    PubMedID: 18059166
  • 1-Aryl-3,5-dihydro-4H-2,3-benzodiazepin-4-ones: novel AMPA receptor antagonists.

    Chimirri A et al (1997) J Med Chem 40(8) : 1258-69.
    PubMedID: 9111300
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