CGP 74514A


Product overview

  • Name
    CGP 74514A
  • Short description
    Selective CDK1 inhibitor
  • Biological description
    Selective CDK1 inhibitor. Shows anti-tumor activity, induces apoptosis and mitochondrial damage.
  • Biological action
  • Citations


  • Chemical name
  • Molecular Weight
  • Chemical structure
    CGP 74514A
  • Molecular Formula
  • PubChem identifier

Storing and Using Your Product

  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for CGP 74514A

  • Induction of apoptosis in human leukemia cells by the CDK1 inhibitor CGP74514A.

    Dai Y et al (2002) Cell Cycle 1(2) : 143-52.
    PubMedID: 12429924
  • The cytotoxic effect of emetine and CGP-74514A studied with the hollow fiber model and ArrayScan assay in neuroendocrine tumors in vitro.

    Larsson DE et al (2012) Anticancer Agents Med Chem 12(7) : 783-90.
    PubMedID: 22263790
  • CDK1 differentially regulates G-overhang generation at leading- and lagging-strand telomeres in telomerase-negative cells in G2 phase.

    Dai X et al (2012) Cell Cycle 11(16) : 3079-86.
    PubMedID: 22871736

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