Chlormezanone

(HB0907)

Product overview

  • Name
    Chlormezanone
  • Short description
    Central muscle relaxant
  • Biological description
    Central muscle relaxant. Binds to GABAA receptor benzodiazepine site. Thought to act as a positive allosteric modulator. Shows anxiolytic actions.
  • Biological action
    Other
  • Purity
    >99%
  • Our products in action

Properties

  • Chemical name
    2-(4-Chlorophenyl)tetrahydro-3-methyl-4H-1,3-thiazin-4-one-1,1-dioxide
  • Molecular Weight
    273.73
  • Chemical structure
    Chlormezanone  [80-77-3]
  • Molecular Formula
    C11H12ClNO3S
  • CAS Number
    80-77-3

Storing and Using Your Product

  • Storage instructions
    room temperature
  • Solubility overview
    soluble in DMSO (100mM) or ethanol (25mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Chlormezanone

  • Comparative study in mice of tetrazepam and other centrally active skeletal muscle relaxants.

    Simiand J et al (1989) Arch Int Pharmacodyn Ther 297 : 272-85.
    PubMedID: 2567153
  • Use of conditioned taste aversion as a conflict model: effects of anxiolytic drugs.

    Ervin GN et al (1988) J Pharmacol Exp Ther 245(1) : 137-46.
    PubMedID: 2896235
  • Interaction of chlormezanone with rat liver microsomes and its degradation.

    Klinger W et al (1997) Eur J Drug Metab Pharmacokinet 22(2) : 165-71.
    PubMedID: 9248786

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