Product overview

Name Chlormezanone
Purity >99%
Description Central muscle relaxant
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Biological Data

Biological description Central muscle relaxant. Binds to GABAA receptor benzodiazepine site. Thought to act as a positive allosteric modulator. Shows anxiolytic actions.

Solubility & Handling

Storage instructions Room temperature
Solubility overview Soluble in DMSO (100mM) or ethanol (25mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Purity >99%
Chemical name 2-(4-Chlorophenyl)tetrahydro-3-methyl-4H-1,3-thiazin-4-one-1,1-dioxide
Molecular Weight 273.73
Chemical structure Chlormezanone  [80-77-3] Chemical Structure
Molecular Formula C11H12ClNO3S
CAS Number 80-77-3
PubChem identifier 2717
SMILES CN1C(C2=CC=C(Cl)C=C2)S(=O)(=O)CCC1=O
InChiKey WEQAYVWKMWHEJO-UHFFFAOYSA-N

References for Chlormezanone

References are publications that support the biological activity of the product
  • Interaction of chlormezanone with rat liver microsomes and its degradation.

    Klinger W et al (1997) Eur J Drug Metab Pharmacokinet 22(2) : 165-71.
  • Comparative study in mice of tetrazepam and other centrally active skeletal muscle relaxants.

    Simiand J et al (1989) Arch Int Pharmacodyn Ther 297 : 272-85.
  • Use of conditioned taste aversion as a conflict model: effects of anxiolytic drugs.

    Ervin GN et al (1988) J Pharmacol Exp Ther 245(1) : 137-46.

3 Item(s)