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Product overview

  • Name
  • Short description
    Potent L- / N-type calcium channel blocker
  • Biological description
    Potent L- and N-type calcium channel blocker (IC50 values are 100 and 200 nM). Inhibits sympathetic neurotransmitter release via N-type Ca2+ channel block. Shows antihypertensive, cardioprotective, renoprotective and neuroprotective actions.
  • Biological action
  • Purity
  • Citations


  • Chemical name
    1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-methoxyethyl(2E)-3-phenyl-2-propenyl ester
  • Molecular Weight
  • Chemical structure
    Cilnidipine  [132203-70-4]
  • Molecular Formula
  • CAS Number

Storing and Using Your Product

  • Storage instructions
  • Solubility overview
    soluble in DMSO (100mM) or ethanol (10mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Cilnidipine

  • Cilnidipine: a new generation Ca channel blocker with inhibitory action on sympathetic neurotransmitter release.

    Takahara A (2009) Cardiovasc Ther 27(2) : 124-39.
    PubMedID: 19426250
  • Effect of cilnidipine, a novel dihydropyridine Ca++-channel antagonist, on N-type Ca++ channel in rat dorsal root ganglion neurons.

    Fujii S et al (1997) J Pharmacol Exp Ther 280(3) : 1184-91.
    PubMedID: 9067302
  • Neuroprotective effects of a dual L/N-type Ca(2+) channel blocker cilnidipine in the rat focal brain ischemia model.

    Takahara A et al (2004) Biol Pharm Bull 27(9) : 1388-91.
    PubMedID: 15340224
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