Product overview

Name Compound E
Purity >98%
Description Potent, selective, non-competitive γ-secretase inhibitor. Induces neuronal differentiation.
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Biological Data

Biological description Cell permeable, potent, selective, non-transition state and non-competitive gamma-secretase inhibitor. Notch processing inhibitor. Only weakly affects presenilinase activity.

Solubility & Handling

Storage instructions +4°C
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Purity >98%
Chemical name (2S)-2-([(3,5-Difluorophenyl)acetyl]amino)-N-[(3S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]propanamide
Molecular Weight 490.5
Chemical structure Compound E [209986-17-4] Chemical Structure
Molecular Formula C27H24F2N4O3
CAS Number 209986-17-4
PubChem identifier 11306390
SMILES C[C@@H](C(N[C@H]1N=C(C2=CC=CC=C2N(C1=O)C)C3=CC=CC=C3)=O)NC(CC4=CC(F)=CC(F)=C4)=O
InChiKey JNGZXGGOCLZBFB-IVCQMTBJSA-N
Appearance White to off-white solid