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CP 94253 hydrochloride

(HB1671)
Data

Product overview

  • Name
    CP 94253 hydrochloride
  • Short description
    Potent, selective 5-HT1B receptor agonist
  • Biological description
    Potent, selective 5-HT1B receptor agonist (Ki values are 2, 89, 49, 860, and 1600 nM at 5-HT1B, 5-HT1A, 5-HT1D, 5-HT1C and 5-HT2 respectively). Reduces foot intake, anticonvulsant and antidepressant-like effects. Active in vivo. Blood-brain barrier permeable.
  • Biological action
    Agonist
  • Purity
    >98%
  • Citations

Properties

  • Chemical name
    5-Propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-pyrrolo[3,2-b]pyridine hydrochloride
  • Molecular Weight
    293.8
  • Chemical structure
    CP 94253 hydrochloride  [845861-39-4]
  • Molecular Formula
    C15H19N3O.HCl
  • CAS Number
    845861-39-4

Storing and Using Your Product

  • Storage instructions
    room temperature (desiccate)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for CP 94253 hydrochloride

  • Effect of 5-HT1B receptor agonists injected into the prefrontal cortex on maternal aggression in rats.

    Veiga CP et al (2007) Braz J Med Biol Res 40(6) : 825-30.
    PubMedID: 17581682
  • Biochemical and behavioral studies of the 5-HT1B receptor agonist, CP-94,253

    Koet et al (1992) Drug dev res 26(3) : 241-250
  • Antidepressant-like effect of the selective 5-HT1B receptor agonist CP 94253: a possible mechanism of action.

    Tatarczyńska E et al (2005) Eur J Pharmacol 516(1) : 46-50.
    PubMedID: 15913599
  • Anticonvulsant effect of the selective 5-HT1B receptor agonist CP 94253 in mice.

    Wesołowska A et al (2006) Eur J Pharmacol 541(1-2) : 57-63.
    PubMedID: 16765343
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