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Product overview

  • Name
  • Short description
    STAT3 inhibitor
  • Biological description
    STAT3 inhibitor (IC50 = 4.6 µM). Also inhibits human acetylcholinesterase (AChE), butyrylcholinesterase (BuChE) and SHP2 (IC50 values are 4.09, 6.38 and 22.5 µM respectively). Shows anti-Alzheimer's disease, anticancer, antidiabetic and antiobesity actions.
  • Alternative names
    CRY; CPT
  • Biological action
  • Purity
  • Citations


  • Chemical name
  • Molecular Weight
  • Chemical structure
    Cryptotanshinone  [35825-57-1]
  • Molecular Formula
  • CAS Number

Storing and Using Your Product

  • Storage instructions
    room temperature
  • Solubility overview
    soluble in DMSO (10mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Cryptotanshinone

  • Antidiabetes and antiobesity effect of cryptotanshinone via activation of AMP-activated protein kinase.

    Kim EJ et al (2007) Mol Pharmacol 72(1) : 62-72.
    PubMedID: 17429005
  • Cryptotanshinone inhibits constitutive signal transducer and activator of transcription 3 function through blocking the dimerization in DU145 prostate cancer cells.

    Shin DS et al (2009) Cancer Res 69(1) : 193-202.
    PubMedID: 19118003
  • Inhibitory effect of cryptotanshinone on angiogenesis and Wnt/β-catenin signaling pathway in human umbilical vein endothelial cells.

    Chen Q et al (2014) Chin J Integr Med 20(10) : 743-50.
    PubMedID: 24740553
  • Cryptotanshinone, an acetylcholinesterase inhibitor from Salvia miltiorrhiza, ameliorates scopolamine-induced amnesia in Morris water maze task.

    Wong KK et al (2010) Planta Med 76(3) : 228-34.
    PubMedID: 19774505
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