In my cart

You have no items in your shopping cart.

Cycloheximide

(HB2904)
Data

Product overview

  • Name
    Cycloheximide
  • Short description
    Eukaryotic protein synthesis inhibitor
  • Biological description

    Widely-used eukaryotic protein synthesis inhibitor. Blocks the elongation phase of translation by binding to the E-site of the 60S ribosomal subunit to block eEF2-mediated tRNA translocation.

    Induces apoptosis in various cells but can also delay or inhibit apoptosis.

    Also inhibits FKBP12 and shows potent antifungal and anti-mold activity.

  • Alternative names
    CHX | Naramycin A
  • Biological action
    Antibiotic
  • Applications
    Cell Culture, Selection Agent
  • Citations

Properties

  • Chemical name
    4-[2-(3,5-Dimethyl-2-oxo-cyclohexyl)-2-hydroxyethyl]-2,6-piperidinedione
  • Molecular Weight
    281.35
  • Molecular Formula
    C15H23NO4
  • CAS Number
    66-81-9
  • PubChem identifier
    6197
  • SMILES
    C[C@H]1C[C@@H](C(=O)[C@@H](C1)[C@@H](CC2CC(=O)NC(=O)C2)O)C
  • InChiKey
    YPHMISFOHDHNIV-FSZOTQKASA-N
  • MDL number
    MFCD00082346
  • Appearance
    White to off-white

Storing and Using Your Product

  • Storage instructions
    Room temperature
  • Solubility overview
    Soluble in ethanol (50 mM) and water (25 mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Support & Resources

Reviews & Product Guides