Product overview

  • Name
    Daidzein
  • Short description
    Estrogen receptors (ER) agonist. Phytoestrogen.
  • Biological description
    Estrogen receptors (ER) agonist. Soy phytoestrogen and genistein analog. Also shows activity at PPARs. Shows both estrogenic/anti-estrogenic activity, induces apoptosis and anticancer effects. Active in vivo.
  • Biological action
    Agonist
  • Purity
    >98%
  • Our products in action

Properties

  • Chemical name
    7-Hydroxy-3-(4-hydroxyphenyl)-4H-1- benzopyran-4-one
  • Molecular Weight
    254.24
  • Chemical structure
    Daidzein [486-66-8]
  • Molecular Formula
    C15H10O4
  • CAS Number
    486-66-8
  • PubChem identifier
    5281708
  • SMILES
    C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3)O)O
  • InChi
    InChI=1S/C15H10O4/c16-10-3-1-9(2-4-10)13-8-19-14-7-11(17)5-6-12(14)15(13)18/h1-8,16-17H
  • InChiKey
    ZQSIJRDFPHDXIC-UHFFFAOYSA-N
  • MDL number
    MFCD00016954

Storing and Using Your Product

  • Storage instructions
    -20°C (desiccate)
  • Solubility overview
    Soluble in DMSO (100mM)

References for Daidzein

  • Isoflavone metabolites and their in vitro dual functions: they can act as an estrogenic agonist or antagonist depending on the estrogen concentration.

    Hwang CS et al (2006) J Steroid Biochem Mol Biol 101(4-5) : 246-53.
    PubMedID: 16965913
  • Daidzein induced apoptosis via down-regulation of Bcl-2/Bax and triggering of the mitochondrial pathway in BGC-823 cells.

    Tang S et al (2013) Cell Biochem Biophys 65(2) : 197-202.
    PubMedID: 22926545
  • Daidzein causes cell cycle arrest at the G1 and G2/M phases in human breast cancer MCF-7 and MDA-MB-453 cells.

    Choi EJ et al (2008) Phytomedicine 15(9) : 683-90.
    PubMedID: 18541420

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