Daminozide

(HB1404)

Product overview

  • Name
    Daminozide
  • Short description
    Selective KDM2/7 histone demethylase inhibitor
  • Biological description
    Selective KDM2/7 JmjC subfamily histone demethylase inhibitor (IC50 values are 0.55, 1.5 and 2.1 µM for PHF8, KDM2A and KDM7A respectively). Plant growth regulator.
  • Alternative names
    N-(dimethylamino)succinamic acid
  • Biological action
    Inhibitor
  • Our products in action

Properties

  • Chemical name
    1-(2,2-Dimethylhydrazide)butanedioi c acid
  • Molecular Weight
    160.17
  • Chemical structure
    Daminozide  [1596-84-5]
  • Molecular Formula
    C6H12N2O3
  • CAS Number
    1596-84-5

Storing and Using Your Product

  • Storage instructions
    room temperature
  • Solubility overview
    soluble in water (100mM) or DMSO (100mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Daminozide

  • Plant growth regulator daminozide is a selective inhibitor of human KDM2/7 histone demethylases.

    Rose NR et al (2012) J Med Chem 55(14) : 6639-43.
    PubMedID: 22724510

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